Selank
Also known as TP-7
A synthetic analog of tuftsin, an immunomodulatory peptide, developed at the Russian Academy of Sciences. Selank provides anxiolytic and nootropic effects without sedation or addiction potential. It enhances cognitive function, reduces anxiety, and modulates immune responses.
| Typical dose | 250-500 mcg |
|---|---|
| Frequency | Once to three times daily (nasal) |
| Half-life | ~5 minutes (rapid CNS uptake) |
| Cycle length | 2-4 weeks on, 2 weeks off |
| Research level | moderate |
| Prescription required | No |
Mechanism of action
Modulates GABA, serotonin, dopamine, and norepinephrine systems. Inhibits enkephalin-degrading enzymes to prolong endogenous opioid signaling. Enhances BDNF expression and stimulates IL-6 production for immune modulation.
What this means in practice
Like Semax, Selank is usually taken intranasally, and the two share a Russian clinical lineage — Selank was developed as an anxiolytic analog of tuftsin. The pairing is common because their effects are reported as complementary rather than additive: Selank toward calm, Semax toward focus. The short half-life means effects are felt and lost within hours, so it tends to be used situationally rather than on a fixed daily schedule.
Reported side effects
- Fatigue (rare)
- Nasal irritation
Commonly stacked with
Track Selank properly
Log doses in one tap, watch the concentration curve update with real half-life math, and score outcomes to see whether it's working. Free, no account.
Get Optim on Google Play →This page is informational and summarises publicly available research. It is not medical advice, not a prescription, and not a recommendation to use any compound. Most compounds described here are not approved by the FDA for human use. Legal status varies by jurisdiction and is yours to determine. Talk to a qualified clinician before starting, stopping, or changing any protocol. For adults 18+. Optim does not sell, source, or recommend suppliers.